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Authors
Wu, Wen-Zhi
Huang, He-Cheng
Zhu, Guang-Hui
Liao, Lian-Di
Chen, Xu-Li
Li, Zhi-Mao
Chu, Man-Yu
Yu, Shuai-Xia
Wang, Dian
Li, En-Min https://orcid.org/0000-0001-6375-3614
Xu, Li-Yan https://orcid.org/0000-0002-1618-4292
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Article History
Received: 4 December 2024
Revised: 4 September 2025
Accepted: 24 September 2025
First Online: 8 October 2025
Competing interests
: The authors of this manuscript are not current editors or Editorial Board Member of British Journal of Cancer. The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this manuscript.
: Patients with ESCC were selected from our nested cohort study registered on the Clinical Trial Management Public Platform, clinical registration number: ChiCTR180001624. Informed consent was obtained from the subject(s) and/or guardian(s). All participants were informed and voluntarily participated in this study and signed an informed consent form. The study was approved by the ethics committee of the Central Hospital of Shantou (2016--026, November 4, 2016), the Ethics Committee of Shantou University Medical College (SUMC-2021--15, March 14, 2021) and the Human Genetic Resources Committee of the Ministry of Science and Technology of China ([2021] CJ1260, [2022 BC0008]. The study was performed in accordance with the Declaration of Helsinki. Ethics related to animal experiments was not addressed in this study.
