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Authors
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Blencowe, Natalie S. https://orcid.org/0000-0002-6111-2175
King, Anni
Shirkey, Beverly
Metcalfe, Chris
Gaunt, Daisy M.
Brierley, Rachel
Boddy, Alex
Higgs, Simon
Dwerryhouse, Simon
Wilkerson, Paul
Berrisford, Richard
Underwood, Tim
Byrne, James
Bowrey, David
Guner, Ali
Peckham-Cooper, Adam
Hollowood, Andrew D.
Koshy, Renol
Wadley, Martin
Jones, Rhys
Powell, Arfon
Hossain, Tanvir
Porter, Heike Cappel
Wong, Newton ACS
Robb, William B.
Hornby, Steven
Barham, C. Paul
Blazeby, Jane M.
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Howes, Ben
Rogers, Chris
Hollingworth, William
Elliott, Jackie
Avery, Kerry
Donovan, Jenny
Culliford, Lucy
Jepson, Marcus
Lamb, Peter
Vohra, Ravinder
Catton, James
Melhado, Rachel
Pursnani, Kishore
Krysztopik, Richard
Alkhaffaf, Bilal
Streets, Christopher
Daniel Titcomb,
Humphreys, Lee
Wheatley, Tim
Sanders, Grant
Ariyarathenam, Arun
Kelly, Jamie
Noble, Fergus
Couper, Graeme
Skipworth, Richard
Deans, Chris
Paisley, Anna
Ubhi, Sukhir
Williams, Rob
Exon, David
Turner, Paul
Shetty, Vinutha
Chaparala, Ram
Akhtar, Khurshid
Parsons, Simon
Welch, Neil
Farooq, Naheed
Hanna, George
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Article History
Received: 25 November 2024
Revised: 31 July 2025
Accepted: 6 October 2025
First Online: 25 November 2025
Competing interests
: The authors declare no competing interests.
: All methods were performed in accordance with the relevant guidelines and regulations. Ethics approval was obtained from NRES Committee South West - Frenchay (ref: 16/SW/0098). The ROMIO trial registration number is ISRCTN10386621. Informed consent was obtained from all patients.
