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Authors
Tsuchida, Shunta
Taki, Tetsuro
Nomura, Kotaro
Suzuki, Kazushi
Hashimoto, Hiroko
Kubota, Shoko
Miyoshi, Tomohiro
Tane, Kenta
Matsumura, Yuki
Samejima, Joji
Aokage, Keiju
Wakabayashi, Masashi
Sasahara, Yukiko
Nagamine, Michiko
Sakashita, Shingo
Sakamoto, Naoya https://orcid.org/0000-0001-6273-0189
Suzuki, Kenji
Tsuboi, Masahiro
Ishii, Genichiro https://orcid.org/0000-0001-8637-3323
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Article History
Received: 14 August 2025
Revised: 21 October 2025
Accepted: 14 November 2025
First Online: 16 December 2025
Competing interests
: Dr. Nomura has received honoraria for lectures from AstraZeneca, Chugai Pharmaceutical Co., Ltd., and Takeda Pharmaceutical Co., Ltd.; honoraria for manuscript writing from Taiho Pharmaceutical Co., Ltd., Nipponrinshosha Co., Ltd., and MedPeer, Inc.; and support for attending meetings and travel from the Chugai Foundation for Innovative Drug Discovery Science. Dr. Wakabayashi has received honoraria for lectures from Nihon Medi-Physics Co., Ltd. Dr. Samejima has received honoraria for presentations from Johnson & Johnson, Osaka Chamber of Commerce and Industry, MiRXES Japan, Taiho Pharmaceutical Co., Ltd., Ziosoft, Olympus, and Japan Blood Products Organization. Dr. Aokage has received honoraria for lectures and/or manuscript writing from various pharmaceutical and medical companies, including AstraZeneca, Chugai, Daiichi Sankyo, Taiho, and others. Dr. Tsuboi has received honoraria for lectures from Johnson & Johnson, AstraZeneca, Chugai, and other pharmaceutical companies. Dr. Ishii has received honoraria for lectures from Roche Diagnostics, Chugai, Novartis, and others. All other authors declare no competing interests.
: This study was approved by the Institutional Review Board of the National Cancer Center Hospital East (approval numbers: 2020-147, 2020-226, and 2024-048), and was conducted in accordance with the Declaration of Helsinki. Comprehensive informed consent was obtained from all study participants.
