Dong, Rui
Srikanth, Akshaya
Tharehalli, Umesh
Seufferlein, Thomas
Schirmbeck, Reinhold
Lechel, André https://orcid.org/0000-0003-0221-6959
Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (Graduiertenkolleg 2254)
Deutsche Forschungsgemeinschaft (Graduiertenkolleg 2254)
Deutsche Forschungsgemeinschaft (Graduiertenkolleg 2254)
Deutsche Forschungsgemeinschaft (Graduiertenkolleg 2254)
Deutsche Forschungsgemeinschaft (Graduiertenkolleg 2254)
Article History
Received: 16 April 2025
Revised: 28 October 2025
Accepted: 14 November 2025
First Online: 15 December 2025
Competing interests
: The authors declare no competing interests.
: All experiments were conducted in accordance with the relevant institutional guidelines and regulations. Animal related experiments were conducted as per the ARRIVE reporting guidelines 2.0 and in accordance with the protocol approved by the Animal Care Committee of the University of Ulm and the Federal Authorities for Animal Research (protocol number 35/9185.81-3, Regierungspraesidium Tuebingen, Baden-Wuerttemberg, Germany). The human data analysed in this study were obtained exclusively from publicly accessible databases, including The Cancer Genome Atlas (TCGA), the Gene Expression Omnibus (GEO), and the Human Protein Atlas (HPA) portal. The IHC images downloaded from the HPA are fully anonymized.