Mukai, Satomi https://orcid.org/0009-0006-7988-6634
Sato, Tatsuhiro https://orcid.org/0000-0002-0689-1794
Kamei, Yasuhiro
Kato, Kagayaki
Mishiro-Sato, Emi https://orcid.org/0000-0001-5528-4440
Kondo-Ida, Lisa
Yabuta, Norikazu
Hiroshima, Kenzo
Sekido, Yoshitaka https://orcid.org/0000-0002-2428-3848
Funding for this research was provided by:
MEXT | Japan Society for the Promotion of Science (24K02336)
MEXT | Japan Society for the Promotion of Science (24K22079)
MEXT | Japan Society for the Promotion of Science (22K07182)
MEXT | Japan Society for the Promotion of Science (25K10503)
Princess Takamatsu Cancer Research Fund
Aichi Cancer Research Foundation
Takeda Science Foundation
Daiko Foundation
Article History
Received: 30 June 2025
Revised: 18 December 2025
Accepted: 19 February 2026
First Online: 6 March 2026
Competing interests
: The authors declare no competing interests.
: This study was approved by the ethics committee of Aichi Cancer Center (approval number IR041047; approval date, September 2022) and performed in accordance with the Declaration of Helsinki. The requirement for informed consent was waived by the ethics committee because of the minimal risk involved. All animal experiments were performed according to the protocols approved by the Institutional Animal Care and Use Committee of the Aichi Cancer Center.