Wang, Zhi
Ingebriktsen, Lise Martine
Bekkhus, Tove
Ma, Lyusong
Queiro-Palou, Antonio
Shi, Wenyang
Bazioti, Anastasia
Panagias, Michail Angelos
Vigorelli, Martina
Lehrstrand, Joakim Harry
Ring, Sarah
Dimberg, Anna
Wik, Elisabeth https://orcid.org/0000-0002-5069-5715
Hoivik, Erling Andre https://orcid.org/0000-0003-0680-765X
Fuxe, Jonas
Ulvmar, Maria H. https://orcid.org/0000-0002-9050-0978
Article History
Received: 19 August 2025
Revised: 26 January 2026
Accepted: 10 March 2026
First Online: 9 April 2026
Competing interests
: The authors declare no competing interests.
: All in vivo procedures were approved by the Uppsala County Regional Ethics Committee (Dnr: 6009/17 MHU and 5.8.18-03169.2023 MHU and 5.8.18-16487/2024 AD). Use of the METABRIC cohorts was approved by the METABRIC Data Access Committee (2015); no additional approvals were required. The approval to use archival biobank LNs was provided by the Uppsala regional ethics committee, 2017/061 and addition 2017/061:1 and 2017/061:2 to MHU. This study was conducted in accordance with the Declaration of Helsinki and the Swedish Ethical Review Act and the Swedish Biobank Act (2023:38) and with approval from Uppsala Biobank. In accordance with the Swedish Biobank Act, all patients were informed about biobank storage and their right to restrict or withdraw consent.
: All authors have provided their consent to publish the manuscript.