Yang, Chenyu https://orcid.org/0000-0002-8590-3297
Ming, Yue
Wu, Qingbin
Ye, Zixia
Duan, Yingying
Ma, Hulin
Xu, Xiaomin
Wei, Rong
Qiu, Xingyang
Yang, Huaping
Yang, Yang
Guo, Jiawei https://orcid.org/0000-0001-5180-3514
Peng, Yong https://orcid.org/0000-0002-1181-3467
Funding for this research was provided by:
National Natural Science Foundation of China (U24A20721)
Article History
Received: 10 September 2025
Revised: 12 March 2026
Accepted: 9 April 2026
First Online: 28 April 2026
Competing interests
: The authors declare no competing interests.
: All animal experiments were approved by the Ethics Committee of West China Hospital, Sichuan University (Approval no. 20250408004). Human CRC and matched adjacent normal tissues were obtained from West China Hospital, Sichuan University, with ethical approval (No. 2019(540)) and informed consent from all patients. All methods were performed in accordance with the relevant guidelines and regulations.