Funding for this research was provided by:
National Natural Science Foundation of China (no. 81771618)
National Natural Science Foundation of China (no. 81971356)
Article History
Received: 26 June 2024
Revised: 14 October 2024
Accepted: 4 December 2024
First Online: 2 January 2025
Competing interests
: The authors declare no competing interests.
: The study was granted approval by the Ethics Review Committee of Renmin Hospital of Wuhan University (approval number: WDRY2022-K277), conducted in accordance with the Helsinki Declaration. Written informed consent was obtained from all enrolled patients. The procedures for care and use of animals were approved by the Ethics Committee of Besser Model Biology Center (approval number: BSMS No. 2023-04-24 A), which adhered to the Guidelines for the Ethical Welfare Review of Laboratory Animals issued by the Ministry of Science and Technology of China (GB/T 35892-2018).