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Pleiotropic mechanisms of cancer-associated fibroblast-mediated resistance in hepatocellular carcinoma: emerging therapeutic vulnerabilities and targeting strategies

Crossref DOI link: https://doi.org/10.1038/s41417-026-01007-w

Published Online: 2026-02-14

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Xie, Wei

Fang, Jingjing

Wang, Zhen

Li, Xia

Du, Juan https://orcid.org/0000-0002-5068-3992
Ling, Changquan
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82374174)

National Natural Science Foundation of China (82074138)
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Text and Data Mining valid from 2026-02-14

Version of Record valid from 2026-02-14
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Article History

Received: 1 October 2025

Revised: 13 December 2025

Accepted: 30 January 2026

First Online: 14 February 2026

Competing interests

: The authors declare no competing interests.

: AI generation or AI-assisted technologies were not used in writing, editing, or revising this article.

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