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Authors
Isermann, Tamara
Schneider, Kim Lucia
Wegwitz, Florian https://orcid.org/0000-0003-0750-6998
De Oliveira, Tiago https://orcid.org/0000-0002-2502-7897
Conradi, Lena-Christin
Volk, Valery
Feuerhake, Friedrich
Papke, Björn
Stintzing, Sebastian
Mundt, Bettina
Kühnel, Florian https://orcid.org/0000-0001-6942-1573
Moll, Ute M.
Schulz-Heddergott, Ramona https://orcid.org/0000-0002-6483-4392
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Funding
Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (SCHU-3160/7-1)
Deutsche Forschungsgemeinschaft (SCHU-3160/6-1)
Einstein Stiftung Berlin (EVF-2018-431-2)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (2R01CA176647)
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Article History
Received: 4 September 2024
Revised: 4 March 2025
Accepted: 21 March 2025
First Online: 9 April 2025
Competing interests
: The authors declare no competing interests.
: Patient tissues for organoid generation were provided by the University Medical Center Göttingen (UMG, Germany) with approval from the ethics committee of UMG for the collection of CRC samples (Approval # 9/8/08 and #25/3/17) and by the Charité – Universitätsmedizin Berlin with approval from the ethics committee of the Charité (Approvals #EA1/161/21 and #EA1/069/113). Animal experiments were approved by the Göttingen University Medical Center Ethics Commission and by the Niedersächsisches Landesamt für Verbraucherschutz und Lebensmittelsicherheit, LAVES, Lower Saxony, Germany.
