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Article History

Received: 27 September 2024

Revised: 25 April 2025

Accepted: 6 May 2025

First Online: 21 May 2025

Competing interests

: The authors declare no competing interests.

: All animal experiments were approved by Animals Care and Use Committee of the Second Affiliated Hospital of Guangzhou Medical University (Approval Number, A2022-042). We designed, performed and reported the experiments in accordance with the Animal Research Reporting of In Vivo Experiments (ARRIVE) guidelines [].

: All authors approved the final manuscript and the submission.