Zhang, Lu https://orcid.org/0000-0002-6788-5515
Qi, Bao
Li, Yanpeng
Liang, Xiao
Zhang, Zifang
Yang, Tao
Jia, Shu
Gao, Xu
Chen, Shang
Jiao, Guangjun
Li, Yangyang
Zhou, Hongming
Chen, Yunzhen https://orcid.org/0000-0001-8447-9001
Li, Yanming
Zhang, Bin https://orcid.org/0000-0002-1282-4846
Li, Gang
Meng, Chunyang https://orcid.org/0000-0002-3334-9503
Article History
Received: 4 January 2025
Revised: 20 May 2025
Accepted: 1 July 2025
First Online: 11 July 2025
Competing interests
: The authors declare no competing interests.
: This experimental plan was approved by the Medical Science Research Ethics Committee of the Affiliated Hospital of Jining Medical University (Approval No. 2023-11-B001). The skeletal tissues that were used for the experiment were all discarded after surgical resection, and the collection of the tissues did not interfere with the treatment plan. BMSCs were extracted from the outflow fluid of the medullary cavity during joint replacement surgery. The collection of surgical specimens was informed to the patients and their families and obtained their consent.