Luan, Yan https://orcid.org/0009-0007-0118-8593
Zhang, Hanyue
Liu, Yingfei
Zhou, Jing
Li, Wen
Ma, Kaige https://orcid.org/0009-0006-3028-4907
Zheng, Xiaoyan
Huang, Chen https://orcid.org/0000-0002-2407-9716
Chen, Xinlin
Lu, Haixia
Yu, Hui
Bjørås, Magnar https://orcid.org/0000-0001-8759-1170
Klungland, Arne https://orcid.org/0000-0001-7274-3661
Zhang, Zhichao https://orcid.org/0000-0001-7990-101X
Article History
Received: 1 April 2025
Revised: 22 July 2025
Accepted: 12 August 2025
First Online: 22 August 2025
Competing interests
: The authors declare no competing interests.
: All methods were performed in accordance with the relevant guidelines and regulations. Mouse experiments were approved by the Institutional Animal Care and Use Committee of Xi’an Jiaotong University (No. XJTUAE2022-445). Mice were housed under standard conditions, which entailed housing in facilities with a 12-h light/dark cycle, ad libitum access to food and water, and a temperature range of 20–24 °C. Stringent measures were taken to mitigate animal suffering and reduce the overall number of animals utilized. We thank the Laboratory Animal Center at Xi’an Jiaotong University for their assistance with housing and breeding experimental mice. This study does not directly involve human subjects or human data that requires ethical approval.