Wang, Huizhi https://orcid.org/0009-0007-9516-4014
Wu, Liuliu
Liu, Chong
Zhao, Xueming
Cui, Luhao
Gao, Jianing
Zhang, Chaonan
Du, Tingting
Shi, Lin
Ji, Yuchen
Xiao, Yilei https://orcid.org/0000-0002-6651-4122
Zhang, Jianguo https://orcid.org/0000-0003-2266-6500
Tu, Wenjun https://orcid.org/0000-0002-1703-1802
Meng, Fangang https://orcid.org/0000-0002-8577-6443
Han, Chunlei https://orcid.org/0000-0002-5724-4466
Article History
Received: 5 February 2025
Revised: 18 August 2025
Accepted: 10 September 2025
First Online: 22 September 2025
Competing interests
: The authors declare no competing interests.
: Human brain tissue samples were collected from patients after written informed consent was obtained from the patients or their legal representatives, and all experimental procedures were performed in accordance with the recognized ethical guidelines of the Declaration of Helsinki, and approval by the Ethics Committee on Human Research at Capital Medical University (Approval No. KY 2021-067-02). All animal experiments were performed in accordance with National Institutes of Health and relevant guidelines for the care and use of laboratory animals of Capital Medical University in China, and approved by Ethics Committee of Capital Medical University (Approval Numbers AEEI-2018-200 and AEEI-2019-097).