Yuan, Qiuyun
Yang, Wanchun
Chen, Siliang
Yuan, Yunbo
Gong, Jingwen
Li, Tengfei
Zuo, Mingrong
Shu, Yuting
He, Yuze
Qin, Yue
Wang, Zhihao
Xia, Xiaoqiang
Cui, Yiyuan
Liu, Yanhui https://orcid.org/0000-0002-3722-3334
Chen, Mina https://orcid.org/0000-0002-7446-3978
Funding for this research was provided by:
National Natural Science Foundation of China (81571195)
National Natural Science Foundation of China (82372836)
National Natural Science Foundation of China (82272644)
Article History
Received: 29 May 2025
Revised: 11 November 2025
Accepted: 2 December 2025
First Online: 12 December 2025
Competing interests
: The authors declare no competing interests.
: All human studies were approved by the Institutional Review Board of West China Hospital of Sichuan University (No. 20241074) and all patients provided written informed consent. For animal works, ethical guidelines for animal experimentation were followed, with approval from the Institutional Animal Care and Use Committees of West China Hospital of Sichuan University (No. 20220228009).