Chen, Fangbing https://orcid.org/0000-0002-4884-4419
Kang, Zhiruo
Liu, Kaiyi
Yang, Wenyi
Lu, Q. Richard
Zhou, Wenhao https://orcid.org/0000-0001-8956-7238
Lin, Yifeng https://orcid.org/0000-0003-4411-8388
Funding for this research was provided by:
CancerFree Kids Foundation
Article History
Received: 8 November 2025
Revised: 10 February 2026
Accepted: 4 March 2026
First Online: 19 March 2026
Competing interests
: The authors declare no competing interests.
: All methods were performed in accordance with the relevant guidelines and regulations. All animal experiments were approved by the Institutional Animal Care and Use Committee (IACUC) of Children’s Hospital of Fudan University (No. 2023-215). All mice used in experiments were maintained in a pathogen-free vivarium with a 12-hour light/dark cycle with free access to normal chow food and water. Stringent measures were taken to mitigate animal suffering and reduce the overall number of animals utilized. This study does not directly involve human subjects or human data that requires ethical approval.