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Authors
Ruan, Yuan
Fan, Pinglong
Zheng, Ruifang
Wu, Xiaolei
Qu, Shanhe
Hu, Kaichao
Zhang, Tianyi
He, Wen bin
Sun, Hongshuo https://orcid.org/0000-0001-5142-1874
Feng, Zhongping
Chu, Shifeng
Zhang, Zhao https://orcid.org/0000-0001-5363-2157
Chen, Naihong https://orcid.org/0000-0001-6354-7853
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Article History
Received: 30 October 2025
Revised: 5 April 2026
Accepted: 27 April 2026
First Online: 12 May 2026
Competing interests
: The authors declare no competing interests.
: All methods were performed in accordance with the relevant guidelines and regulations. All animal experimental procedures in this study were conducted in accordance with the ARRIVE guidelines and were approved by the Laboratory Animal Ethics Committee of the Chinese Academy of Medical Sciences and Peking Union Medical College (Ethics Approval No.: IMM-S-25-0320) prior to study initiation. This study involving human subjects was approved in advance by the Institutional Review Board (IRB) of Beijing Hospital of Integrated Traditional Chinese and Western Medicine (Ethics Approval No.: ZXYEC-KT-2025-45-P01). All human-related procedures were conducted in accordance with the Declaration of Helsinki and relevant ethical guidelines. Prior to the initiation of the study, written informed consent was obtained from all participants or their legally authorized representatives, who voluntarily participated after fully understanding the study objectives, procedures, potential risks, and anticipated benefits. Additional written informed consent was obtained from all participants for the publication of any identifiable images related to this manuscript.
