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Alternative splicing of ceramide synthase 2 alters levels of specific ceramides and modulates cancer cell proliferation and migration in Luminal B breast cancer subtype

Crossref DOI link: https://doi.org/10.1038/s41419-021-03436-x

Published Online: 2021-02-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Pani, Trishna

Rajput, Kajal

Kar, Animesh https://orcid.org/0000-0003-4078-5677
Sharma, Harsh

Basak, Rituparna

Medatwal, Nihal https://orcid.org/0000-0002-3273-9315
Saha, Sandhini

Dev, Gagan

Kumar, Sharwan

Gupta, Siddhi

Mukhopadhyay, Arnab https://orcid.org/0000-0002-5266-7849
Malakar, Dipankar

Maiti, Tushar Kanti

Arimbasseri, Aneeshkumar G.

Deo, S. V. S.

Sharma, Ravi Datta

Bajaj, Avinash

Dasgupta, Ujjaini https://orcid.org/0000-0002-2281-078X
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Text and Data Mining valid from 2021-02-10

Version of Record valid from 2021-02-10
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Article History

Received: 8 April 2020

Revised: 12 January 2021

Accepted: 13 January 2021

First Online: 10 February 2021

Ethics approval

: Patient tumor and adjoining normal breast tissue were collected from operable breast cancer Luminal B patients (Stages I, II, IIIa) undergoing treatment at Dr. B. R. Ambedkar Institute-Rotary Cancer Hospital (BRA-IRCH), All India Institute of Medical Sciences (AIIMs), New Delhi, and from biorepository of Rajiv Gandhi Cancer Institute and Research Center (RGCIRC), Delhi after due Ethical clearance from AIIMS (IEC-332/01.07.2016), RGCIRC (RGCIRC/IRB/276/2019, Res/BR/TRB-20/2020/70), and Amity University Haryana (IEC-AIISH/AUH/2016-1).

: The authors declare that they have no conflict of interest.

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