Liu, Muyun
Wang, Dan
Luo, Yongde
Hu, Lianghao
Bi, Yawei
Ji, Juntao
Huang, Haojie
Wang, Guoqiang
Zhu, Liang
Ma, Jianjia
Kim, Eunice
Luo, Catherine K.
Abbruzzese, James L.
Li, Xiaokun
Yang, Vincent W.
Li, Zhaoshen
Lu, Weiqin https://orcid.org/0000-0002-6491-8203
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Cancer Institute (1R01CA240818-01A1)
U.S. Department of Defense (W81XWH-20-1-0625)
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (1R01DK123079-01, 1R56DK123079-01)
U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases
SUNY | Stony Brook University (SUNY Central Award, DoM Pilot Project Award, Start-up Fund)
National Natural Science Foundation of China (81270540, 81670585)
Article History
Received: 7 October 2020
Revised: 14 January 2021
Accepted: 19 January 2021
First Online: 16 February 2021
Ethics statement
: All procedures for generating and experimenting with the <i>fElas</i><sup><i>CreERT</i></sup><i>;Kras</i><sup><i>LSL-G12D/+</i></sup> and <i>fElas</i><sup><i>CreERT</i></sup><i>;Kras</i><sup><i>LSL-G12D/+</i></sup><i>;Trp53</i><sup><i>LSL-R172H/+</i></sup> mouse models were reviewed and approved by the Stony Brook University Institutional Animal Care and Use Committee (IACUC). The generation and experimental use of KPC cell xenograft mouse models were reviewed and approved by the IACUC at Changhai Hospital.
: This work was supported by 1R56DK123079-01, 1R01DK123079-01, and 1R01CA240818-01A1 from the NIH, W81XWH-20-1-0625 from the DoD, a Start-up Fund and a SUNY Central Award from Stony Brook University, and a Pilot Project Grant from the Department of Medicine at Stony Brook University to W.L., as well as the National Natural Science Foundation of China (81270540 and 81670585) to Z.L.
: The authors declare that they have no conflict of interest.