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Article History

Received: 26 March 2021

Revised: 2 September 2021

Accepted: 15 September 2021

First Online: 12 October 2021

Competing interests

: The authors declare no competing interests.

: All procedures performed in studies involving human participants were in accordance with the standards upheld by the Ethics Committee of Shanghai Jiao Tong University Affiliated Sixth People’s Hospital and with those of the 1964 Helsinki Declaration and its later amendments for ethical research involving human subjects. All animal experiments were approved by the Ethics Committee of Shanghai Jiao Tong University Affiliated Sixth People’s Hospital for the use of animals and conducted in accordance with the National Institutes of Health Laboratory Animal Care and Use Guidelines. Written informed consent was obtained from a legally authorized representative(s) for anonymized patient information to be published in this article.