Zhu, Zhenru https://orcid.org/0000-0001-6991-0414
Cao, Chuanhui
Zhang, Dongyan
Zhang, Zhihong https://orcid.org/0000-0002-9771-1313
Liu, Li https://orcid.org/0000-0002-5265-4159
Wu, Dehua https://orcid.org/0000-0003-0560-0016
Sun, Jingyuan https://orcid.org/0000-0003-3485-0567
Funding for this research was provided by:
National Natural Science Foundation of China (81903133)
National Natural Science Foundation of China (81902478)
National Natural Science Foundation of China (82073343)
National Natural Science Foundation of China (81972897)
National Natural Science Foundation of China (82073394)
China Postdoctoral Science Foundation (2020M672736)
Medical Science and Technology Foundation of Guangdong Province (2021A1515012151)
Medical Science and Technology Foundation of Guangdong Province (2017A030310105)
Natural Science Foundation of Guangdong Province (2019A1515011436)
Guangzhou Municipal Science and Technology Project (No.201906010087)
Article History
Received: 12 March 2021
Revised: 16 December 2021
Accepted: 28 January 2022
First Online: 15 February 2022
Competing interests
: The authors declare no competing interests.
: All procedures involving animals were approved by the ethics committee of the Southern Medical University and followed the NIH’s Guide for the Care and Use of Laboratory Animals (8th ed., National Academies Press, 2011). All studies associated with patients’ samples were approved by the ethics committee of Nanfang Hospital (ID: NFEC-2012-K3), and informed consent was obtained from all patients.