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Article History

Received: 28 February 2023

Revised: 19 July 2023

Accepted: 31 July 2023

First Online: 8 August 2023

Competing interests

: The authors declare no competing interests.

: The experiments with patient samples were conducted in accordance with the Helsinki Declaration with ethical approval from the Hunter New England Human Research Ethics Committee (approval number: 09/05/20/5.02) and the University of Newcastle Health and Safety Committee (approval number: R7/2021). The experiments with animals were reviewed, approved, and carried out according to the Animal Care and Ethics Committee of the University of Newcastle (approval number: A-2020-016).