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Hypoxia-induced DTL promotes the proliferation, metastasis, and sorafenib resistance of hepatocellular carcinoma through ubiquitin-mediated degradation of SLTM and subsequent Notch pathway activation

Crossref DOI link: https://doi.org/10.1038/s41419-024-07089-4

Published Online: 2024-10-09

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Chen, Zi-Xiong

Mu, Mao-Yuan

Yang, Guang

Qi, Han

Fu, Xiao-Bo

Wang, Gui-Song

Jiang, Wei-Wei

Huang, Bi-Jun https://orcid.org/0000-0001-6816-1503
Gao, Fei https://orcid.org/0000-0002-4086-2575
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Article History

Received: 1 December 2023

Revised: 11 September 2024

Accepted: 17 September 2024

First Online: 9 October 2024

Competing interests

: The authors declare no competing interests.

: The study protocol was authorized by the Ethics Committee of Sun Yat-sen University Cancer Center (Guangzhou, China), and written informed consent was obtained from all participants.

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