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Authors
Vasquez, Velmarini
Kodavati, Manohar
Mitra, Joy
Vedula, Indira
Hamilton, Dale J. https://orcid.org/0000-0002-2481-2746
Garruto, Ralph M.
Rao, K. S.
Hegde, Muralidhar L. https://orcid.org/0000-0001-7333-8123
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Funding
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (RF1NS112719)
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Article History
Received: 19 February 2024
Revised: 15 November 2024
Accepted: 21 November 2024
First Online: 18 December 2024
Competing interests
: The authors declare no competing interests.
: Human postmortem brain tissue from Guam PD, Guam ALS, and age-matched Guam non-neurological controls were sourced from the Binghamton Biorepository Archive (ALS-Guam). These samples were obtained as de-identified frozen specimens. The studies involving human samples were conducted in accordance with the ethics board standards at the Binghamton Biorepository Archive (ALS-Guam) and the institutional review boards at the Houston Methodist Research Institute (protocol IBC00001560). Additionally, experiments involving non-neurological control and PD patient-derived neural progenitor cells (hNPSCs) were approved by the institutional review boards at the Houston Methodist Research Institute (protocol IBC00001560).
