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Authors
Li, Sijing
Mingoia, Silvia
Montégut, Léa https://orcid.org/0000-0003-4778-4757
Lambertucci, Flavia
Chen, Hui https://orcid.org/0000-0002-1260-8617
Dong, Yanbing
De Palma, Fatima Domenica Elisa https://orcid.org/0000-0002-6109-2768
Scuderi, Sarah Adriana
Rong, Yan
Carbonnier, Vincent
Martins, Isabelle
Maiuri, Maria Chiara https://orcid.org/0000-0001-9760-7674
Kroemer, Guido https://orcid.org/0000-0002-9334-4405
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Funding
Funding for this research was provided by:
Agence Nationale de la Recherche (21-ESRE-0028)
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Article History
Received: 7 October 2024
Revised: 14 January 2025
Accepted: 11 February 2025
First Online: 26 February 2025
Competing interests
: IM consults for Osasuna Therapeutics. GK has been holding research contracts with Daiichi Sankyo, Eleor, Kaleido, Lytix Pharma, PharmaMar, Osasuna Therapeutics, Samsara Therapeutics, Sanofi, Sutro, Tollys, and Vascage. GK is on the Board of Directors of the Bristol Myers Squibb Foundation France. GK is a scientific co-founder of everImmune, Osasuna Therapeutics, Samsara Therapeutics and Therafast Bio. GK is in the scientific advisory boards of Hevolution, Institut Servier, Longevity Vision Funds and Rejuveron Life Sciences. GK is the inventor of patents covering therapeutic targeting of aging, cancer, cystic fibrosis and metabolic disorders. GK’s wife, Laurence Zitvogel, has held research contracts with Glaxo Smyth Kline, Incyte, Lytix, Kaleido, Innovate Pharma, Daiichi Sankyo, Pilege, Merus, Transgene, 9 m, Tusk and Roche, was on the on the Board of Directors of Transgene, is a cofounder of everImmune, and holds patents covering the treatment of cancer and the therapeutic manipulation of the microbiota. GK’s brother, Romano Kroemer, was an employee of Sanofi and now consults for Boehringer-Ingelheim. The funders had no role in the design of the study; in the writing of the manuscript, or in the decision to publish the results.
: Human ethics approval was not needed; this study was achieved in silico with publicly available data. Mouse experiments were performed in accordance with the FELASA guidelines and under the agreement by the local Animal Experimental Ethics Committee (project number #25355-2020050715057113v4).
