Funding for this research was provided by:
National Natural Science Foundation of China (32100656, 32100656, 32100656, 32100656, 32100656)
Article History
Received: 16 November 2024
Revised: 17 April 2025
Accepted: 6 May 2025
First Online: 19 May 2025
Competing interests
: The authors declare no competing interests.
: All methods were performed in accordance with the relevant guidelines and regulations. This study was approved by the Medical Ethical Committee of Qilu Hospital of Shandong University (approval number: KYLL-2023 (ZM)-466) and informed consent was obtained from all participants. This study did not involve any interventional clinical trial. Animal protocols were approved by the Animal Ethics Committee of Qilu Hospital of Shandong University (approval number: DWLL-202400161).