Daniel, Yoann https://orcid.org/0000-0002-5327-553X
Rauch, Claudine
Moutaux, Lucille
Desquilles, Lise https://orcid.org/0000-0002-1534-3044
Le Charpentier, Tifenn
Fekir, Karim https://orcid.org/0000-0001-8120-6171
Cano, Luis https://orcid.org/0000-0002-3417-8750
Catheline, Daniel
Pierre, Servane
Burel, Agnès https://orcid.org/0000-0003-2990-3345
Savary, Camille https://orcid.org/0000-0003-3281-6744
Ribault, Catherine
Bendavid, Claude https://orcid.org/0000-0003-2459-9567
Clément, Bruno https://orcid.org/0000-0001-8827-146X
Aninat, Caroline https://orcid.org/0000-0002-9008-0686
Rioux, Vincent https://orcid.org/0000-0001-9837-1675
Musso, Orlando https://orcid.org/0000-0001-8881-6925
Fromenty, Bernard https://orcid.org/0000-0003-2994-5465
Cabillic, Florian https://orcid.org/0000-0001-7204-5652
Corlu, Anne https://orcid.org/0000-0002-7370-0564
Funding for this research was provided by:
Ligue Contre le Cancer
Institut National Du Cancer (12688)
Institut National Du Cancer (12688)
Institut National Du Cancer (12688)
Université de Rennes
Université de Rennes 1
Institut National de la Santé et de la Recherche Médicale
Région Bretagne
Région Bretagne Université de Rennes
institut agro Rennes Angers
Uuniveisté de Rennes
European Union’s Horizon 2020 Research and Innovation Program,
Centre National de la Recherche Scientifique
Université de Rennes European Union’s Horizon 2020 Research and Innovation Program,
Article History
Received: 9 December 2024
Revised: 16 May 2025
Accepted: 16 June 2025
First Online: 17 November 2025
Competing interests
: The authors declare no competing interests.
: Human tissue samples were processed by the Biological Resource Center, Rennes University Hospital (BB-0033-00056) after sample examination by the Anatomic Pathology laboratory. The study protocol complied with French laws and regulations and was approved by INSERM’s Institutional Review Board (number 19-630) in the context of the National Network of Liver Biological Resource Centers. Sample collection was reported to the Ministry of Education and Research (no. DC-2008-338). All the patients provided written informed consent.