Cave, Donatella Delle https://orcid.org/0000-0002-4019-2778
Di Domenico, Annalisa
Fantuz, Marco https://orcid.org/0000-0001-7758-3660
Ciotola, Marianna
Mangini, Maria
Buonaiuto, Silvia
Corrado, Brunella
Corona, Marco
Saracino, Federica
Andolfi, Gennaro
Di Biase, Ilaria
Cucciardi, Antonio
Carrer, Alessandro https://orcid.org/0000-0002-9300-6879
Sainz, Bruno Jr https://orcid.org/0000-0003-4829-7651
Pirozzi, Teresa
Re, Daniele Lo
Colonna, Vincenza
Minchiotti, Gabriella https://orcid.org/0000-0003-0225-9043
De Luca, Anna Chiara https://orcid.org/0000-0002-3696-8465
Lonardo, Enza https://orcid.org/0000-0001-6654-1043
Funding for this research was provided by:
Fondazione Italiana per la Ricerca sul Cancro (30710, 23029, 21420, 27012)
Fondazione Umberto Veronesi
World Cancer Research Fund (20-0188)
Article History
Received: 30 December 2024
Revised: 30 April 2025
Accepted: 3 July 2025
First Online: 6 August 2025
Competing interests
: The authors declare no competing interests.
: All animal experiments were approved by the Italian Ministry of Health (IACUC protocol n°1010/2023-PR) prior to the commencement of the study. All the procedures were performed in the animal facility at IGB-CNR under pathogen-free conditions in accordance with Regulations for the Council Directive 2010/63/EU on the protection of animals used for scientific and experimental purposes. The IGB-CNR animal facility is authorized by the Ministry of Health according to the Italian law on animal experimentation (D.L. 26/2014). All experiments were performed in accordance with the approved protocol and the relevant guidelines and regulations.