Ji, Xingzhao
Xue, Fuyuan
Wang, Ying
Gao, Dexuan
Sun, Jian
Dong, Tianyi
Mu, Qian https://orcid.org/0000-0002-9839-1980
Xu, Quanlin
Sun, Shengnan
Liu, Yi https://orcid.org/0000-0002-4094-2663
Wan, Qiang https://orcid.org/0000-0001-9173-2941
Funding for this research was provided by:
National Natural Science Foundation of China (82370725, 82070756, 82371604, 82200049, 82101639, 82071569, 82271622, 82471621)
Natural Science Foundation of Shandong Province (ZR2021QH193)
Article History
Received: 28 October 2024
Revised: 23 June 2025
Accepted: 15 July 2025
First Online: 26 August 2025
Competing interests
: The authors declare no competing interests.
: Animal studies were performed accordance with the Basel Declaration and were approved by the ethics committee of the Shandong Provincial Hospital (NSFC: NO 2021-099). The protocol for tissue collection was accordance with the Helsinki Declaration, written informed consent was obtained from all patients and was approved by the Ethical Committee of Shandong Provincial Hospital (NSFC: NO 2021-099).