Chen, Jhen-Yu
Ke, Tao-Wei
Chiang, Shu-Fen
Hong, Wei-Ze
Chang, Hsin-Yu
Liang, Ji-An
Tsai, Yuan-Yao
Huang, Chi-Hsien
Chen, William Tzu-Liang
Chao, K. S. Clifford https://orcid.org/0000-0002-7162-2566
Huang, Kevin Chih-Yang https://orcid.org/0000-0002-0266-3233
Funding for this research was provided by:
China Medical University Hospital (DMR-112-197)
Ministry of Science and Technology, Taiwan (MOST110-2628-B-039-005)
Ministry of Science and Technology, Taiwan (MOST110-2314-B-039-032)
Article History
Received: 23 January 2025
Revised: 30 June 2025
Accepted: 22 July 2025
First Online: 1 August 2025
Competing interests
: The authors declare no competing interests.
: All methods were carried out in accordance with the relevant ethical guidelines and regulations. Tissue collection was approved by the Institutional Review Board (IRB) of China Medical University Hospital [Protocol number: CMUH107-REC2-008]. The animal care and experimental procedures were approved by the China Medical University Animal Care Committee (CMUIACUC-2018-182). Efforts were made to minimize animal suffering and reduce the number of animals used.
: Informed consent was obtained from all human participants or their legal guardians in accordance with the Declaration of Helsinki.