Su, Guoqing
Qian, Jinghang
Wang, Yi
Zhu, Yu
Chen, Yanyan
Shen, Jingru
Jiang, Jiayuan
Cao, Yuepeng
Wang, Nannan
Huang, Xing https://orcid.org/0000-0001-9982-8622
Si, Chengshuai
Zhang, Xu
Shao, Peng
Ye, Yongxia
Wang, Yang
Bao, Jun
Yang, Liu https://orcid.org/0000-0002-5961-1469
Funding for this research was provided by:
National Natural Science Foundation of China (81602145, 82072704, 82203868)
Article History
Received: 11 February 2025
Revised: 24 June 2025
Accepted: 28 July 2025
First Online: 7 August 2025
Competing interests
: The authors declare no competing interests.
: Animal Studies: Animal studies were approved by the Institutional Animal Care and Use Committee of Nanjing Medical University (No. IACUC-2211031). All animal studies were complied with the ARRIVE guidelines and were conducted in accordance with the UK Animals (Scientific Procedures) Act, 1986 and associated guidelines, EU Directive 2010/63/EU for animal experiments, or the National Institutes of Health Guide for the care and use of Laboratory animals (NIH Publications No. 8023, revised 1978). Experiments involving humans were in accordance with the ethical standards of the committee (institution and national) and with The Code of Ethics of the World Medical Association (Declaration of Helsinki). All patients completed written informed consent prior to study entry. This study protocol was reviewed and approved by the Ethics Committee of Jiangsu Cancer Hospital, located in Nanjing, Jiangsu Province, China.