Dian, Meijuan
Yun, Liang
Meng, Qingyu
Lin, Songwen
Ji, Ming
Zhou, Ying
Liu, Wenqian
Yang, Zhuoying
Zhao, Yayan
Li, Gaoyuan
Jiang, Jianjun
Hao, Weichao https://orcid.org/0000-0003-4973-1173
Chen, Zhijie
Zhou, Zehao
Zhang, Ruihao
Liu, Tianyuan https://orcid.org/0000-0001-7367-8128
He, Yujing
Yan, Tianbao
Wang, Haofei
Cronin, Shane J. F. https://orcid.org/0000-0003-4222-5315
Penninger, Josef M. https://orcid.org/0000-0002-8194-3777
Cai, Kaican https://orcid.org/0000-0002-6805-4107
Rao, Shuan https://orcid.org/0000-0002-5268-7006
Funding for this research was provided by:
National Natural Science Foundation of China (82072587, 82203430, 82304977, 82273456)
CACMS | Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences and Peking Union Medical College (2022-PUMCH-D-001)
OeAD-GmbH (CN03/2021)
Gouvernement du Canada | Instituts de Recherche en Santé du Canada | CIHR Skin Research Training Centre (FRN 168899)
Article History
Received: 3 March 2025
Revised: 29 July 2025
Accepted: 19 August 2025
First Online: 30 August 2025
Competing interests
: The authors declare no competing interests.
: The study was carried out in compliance with the Declaration of Helsinki, and the research protocol received approval from the Medical Ethics Committee of Nanfang hospital of Southern Medical University. Written informed consent was obtained from all participants prior to the use of tissue samples for scientific purposes. All animal experimental procedures were conducted in accordance with protocols approved by the Institutional Animal Care and Use Committee of Southern Medical University Nanfang Hospital. All methods were performed in accordance with the relevant guidelines and regulations.