Ying, Leqian https://orcid.org/0000-0001-9846-6527
Zhu, Yini https://orcid.org/0000-0002-9592-2053
Zhang, Lu
Ji, Min
Wang, Meidan
Dong, Lei
Yun, Zhengcheng
Chen, Yanping
Zhou, Jingyi
Huang, Chunchun
Zhang, Shengwei
Yang, Xuhong
Yang, Hui
Huang, Guichun https://orcid.org/0000-0002-4757-2626
Qin, Shukui
Xie, Jinbing https://orcid.org/0000-0002-6071-0878
Funding for this research was provided by:
Bethune Charitable Foundation
National Natural Science Foundation of China (82403285, 82372023, 82172010)
Article History
Received: 7 April 2025
Revised: 1 August 2025
Accepted: 28 August 2025
First Online: 6 October 2025
Competing interests
: The authors declare no competing interests
: This study was conducted in compliance with the Declaration of Helsinki. Written informed consent was obtained from all participants, and the study protocol was approved by the Clinical Research Ethics Committee of Zhongda Hospital, Affiliated to Southeast University (#2022ZDSYLL273-P01; April 1, 2022). All animal experimental procedures were approved by the Institutional Animal Care and Use Committee of Southeast University (#20240103004; January 3, 2024).