Huska, Jason D.
Doyle, Kelly J.
Purkal, Julie J.
Hrusch, Cara L.
Duggan, Ryan C.
Boghaert, Erwin R.
Souers, Andrew J. https://orcid.org/0009-0002-5965-0633
Phillips, Darren C.
Tahir, Stephen K. https://orcid.org/0009-0004-7932-0353
Article History
Received: 14 June 2024
Revised: 23 July 2025
Accepted: 1 September 2025
First Online: 16 October 2025
Competing interests
: All authors either are or were employees of AbbVie. The design, study conduct, and financial support for this research were provided by AbbVie. AbbVie participated in the interpretation of data, review, and approval of the publication. KJD, JJP, CLH, RCD, ERB, DCP, AJS & SKT are stockholders of AbbVie Inc.
: All methods were performed in accordance with the relevant guidelines and regulations. All mice protocols were approved by the Institutional Animal Care and Uses Committee (IACUC) at AbbVie Inc. and performed in accordance with National Institutes of Health Guide for the Care and Use of Laboratory Animals.