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Authors
Vaccarella, Sebastiano https://orcid.org/0009-0005-1937-4699
Bruno, Valentina https://orcid.org/0000-0002-0008-9573
Orlandi, Giulia
Covino, Daniela Angela
Frascolla, Carlotta
Pulito, Claudio https://orcid.org/0000-0002-0921-6962
Vizza, Riccardo https://orcid.org/0009-0000-7401-8965
Urbani, Giulia
Allegretti, Matteo https://orcid.org/0000-0003-3398-8775
De Pascale, Valentina
Goeman, Frauke https://orcid.org/0000-0002-7803-8821
Ciuffreda, Ludovica https://orcid.org/0000-0002-7964-7119
Arteni, Brindusa Ana Maria
Di Martino, Simona
Sacconi, Andrea https://orcid.org/0000-0002-8276-0438
Mancini, Emanuela
Bagnato, Anna
Baiocco, Ermelinda
Kajal, Ramy
Vinik, Yaron
Lev, Sima https://orcid.org/0000-0002-2108-3330
Fanciulli, Maurizio https://orcid.org/0000-0002-5281-4191
Vidiri, Antonello
Carosi, Mariantonia https://orcid.org/0000-0002-6298-7168
Strano, Sabrina
Donzelli, Sara https://orcid.org/0000-0002-8529-2895
Vizza, Enrico
Blandino, Giovanni https://orcid.org/0000-0002-6970-2241
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Funding
Funding for this research was provided by:
Ministero della Salute (MUR-PNRR M4C2I1.3 PE6 project PE00000019 Heal Italia (CUP H83C22000550006))
Ministero della Salute (PNRR – M6/C2_CALL 2023, project PNRR-MCNT1-2023-12378252)
Ministero della Salute (Ricerca Corrente 2024 (CUP H83C24000170001))
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Article History
Received: 9 July 2025
Revised: 18 August 2025
Accepted: 4 September 2025
First Online: 28 November 2025
Competing interests
: The authors declare no competing interests.
: All methods were performed in accordance with the relevant guidelines and regulations. Generation of patient-derived organoids from EC was approved by institutional review board of Regina Elena National Cancer Institute and appropriate regulatory authorities (approval no. IFO 1777/22). All patients signed an informed consent.
