Article History
Received: 4 September 2024
Revised: 24 August 2025
Accepted: 11 September 2025
First Online: 16 October 2025
Competing interests
: The authors declare no conflict of interest.
: All the recruited patients signed informed consents. All of the protocols met the ethical guidelines of the Helsinki Declaration and approved by the Medical Ethics Committees of Shandong University and Shandong Provincial Hospital.