Chen, Hui
Guan, Qiujing
Yang, Cheng
Chen, Yang
Liu, Yan
Ren, Wenjie
Chen, Su
Li, Lei https://orcid.org/0000-0002-3114-1653
Li, Dongxia https://orcid.org/0009-0000-1915-7508
Tang, Jianguo https://orcid.org/0000-0003-1263-7327
Zhong, Nanzhe https://orcid.org/0000-0002-9808-2280
Funding for this research was provided by:
Natural Science Foundation of Chongqing (CSTB2024NSCQ-JQX0009)
National Natural Science Foundation of China (82372456, 81902731)
Shanghai Pilot Program for Basic Researc
Talent Development Project of Shanghai Fifth People’s Hospita
Foundation of Shanghai Municipal Commission of Health and Family Planning (201840209)
Shanghai Minhang District Health and Family Planning Commission
Sailing Talent Program of Navy Medical University
Article History
Received: 24 February 2025
Revised: 22 August 2025
Accepted: 17 September 2025
First Online: 24 October 2025
Competing interests
: The authors declare no competing interests.
: This study was approved by the Research Ethics Committees of The Second Affiliated Hospital of Naval Medical University (approval number 2018SL015), and written informed consent for clinical data and tissue collection was obtained from all patients or their legal guardians, and all personal identifying information has been anonymized. All methods were performed in accordance with the relevant guidelines and regulations.
: All authors agree to the content of the paper and are listed as co-authors of the paper.