He, Siyi
Meister, Daniel
Khan, Samra
Mohammadzadeh, Azam
Delgadillo Silva, Luis https://orcid.org/0000-0002-2721-5920
Rutter, Guy A.
Trant, John F. https://orcid.org/0000-0002-4780-4968
Lim, Gareth E. https://orcid.org/0000-0003-3850-3757
Article History
Received: 14 October 2024
Revised: 16 September 2025
Accepted: 13 October 2025
First Online: 10 November 2025
Competing interests
: SH, DM, and LD have nothing to disclose. GEL was a consultant for Diogenix and Ambagon Therapeutics and has received research funding from Inversago Pharma, a Novo Nordisk Company. GAR has received grant funding from, and is a consultant for, Sun Pharmaceuticals Inc. JFT is CEO of Binary Star Research Services, which has no interests in the subject of this work, holds no relevant IP, and neither received, nor provided, any funding associated with this work. BSRS had no input into the methods used, or the conclusions of this work.
: All experiments were done in accordance with the rules and regulations and guidelines of the Centre de Recherche du Centre hospitalier de l’Université de Montréal (CRCHUM) and the University of Windsor.