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Site-specific HPV18 integration facilitates cervical carcinogenesis through metabolic reprogramming-induced dysfunction of the SpHK1/S1P/S1PR1 pathway

Crossref DOI link: https://doi.org/10.1038/s41419-025-08195-7

Published Online: 2026-01-09

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wang, Liming

Li, Xiaomin

Ren, Ci

Liu, Liting

Yao, Jiaying

Wu, Min

Shen, Hui

Zhu, Da

Wang, Xiaoli https://orcid.org/0000-0002-0264-5131
Yuan, Zan https://orcid.org/0000-0001-5582-5120
Huang, Yafei

Wang, Hui https://orcid.org/0000-0001-6789-5185
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82373260)

National Natural Science Foundation of China (82472696)

National Natural Science Foundation of China (82273211)
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Text and Data Mining valid from 2026-01-09

Version of Record valid from 2026-01-09
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Article History

Received: 3 May 2025

Revised: 26 September 2025

Accepted: 22 October 2025

First Online: 9 January 2026

Competing interests

: The authors declare no competing interests.

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