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Authors
Xia, Yuan https://orcid.org/0000-0002-8061-4955
Zhu, Jianfeng https://orcid.org/0000-0002-3585-6701
Guo, Rui
Shen, Xuxing https://orcid.org/0000-0003-0110-1463
Shi, Min
Shen, Na
Fan, Lei https://orcid.org/0000-0002-9368-4987
Chen, Lijuan https://orcid.org/0000-0002-6497-1194
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Article History
Received: 17 May 2025
Revised: 23 October 2025
Accepted: 31 October 2025
First Online: 19 December 2025
Competing interests
: The authors declare no competing interests.
: This study was conducted in accordance with the Declaration of Helsinki and approved by the Institutional Review Boards of the First Affiliated Hospital of Nanjing Medical University Ethics Committee (No. 2023-SR-011). Informed consent was obtained from all participants prior to enrollment. All animal care and experimental procedures complied with the Guidelines for the Care and Use of Laboratory Animals of Nanjing Medical University, and were approved by Institutional Animal Care and Use Committee (IACUC) of Nanjing Medical University (No. 2201014).
