Zhao, Hui https://orcid.org/0009-0003-3521-2839
Yu, Xueying
Jiang, Minxin
Li, Ziqi
Zhao, Yanyu
Ren, Yuxin
Fang, Lanlan
Wang, Mengmeng
Lu, Xiaofeng
Ma, Yubo
Wang, Guosheng
Zhou, Qiang
Zou, Yanfeng https://orcid.org/0000-0002-2327-6718
Cai, Guoqi https://orcid.org/0000-0002-6481-704X
Pan, Faming https://orcid.org/0000-0003-4242-1025
Funding for this research was provided by:
National Natural Science Foundation of China (82073655)
National Natural Science Foundation of China (82373672)
National Natural Science Foundation of China (82373657)
Research Innovation Team Project of School of Public Health Anhui Medical University
the Anhui Medical University Basic and Clinical Collaborative Research Enhancement Program
the Scientific Research Promotion Plan of Anhui Medical University
Article History
Received: 18 May 2025
Revised: 16 October 2025
Accepted: 3 November 2025
First Online: 8 January 2026
Competing interests
: The authors declare no competing interests.
: This study was approved by the Ethics Committee of Anhui Medical University (No. 83230287). All animal experiments performed in this study were approved by the Laboratory Animal Ethics Committee of Anhui Medical University (LLSC20220653). All methods were performed in accordance with the relevant guidelines and regulations.
: Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.