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Inhibition of glycolysis and stimulation of mitochondrial biogenesis lead to increased ROS levels and cell death in HNF-1ß positive clear cell carcinoma

Crossref DOI link: https://doi.org/10.1038/s41419-025-08243-2

Published Online: 2025-12-01

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Kawahara, Naoki https://orcid.org/0000-0003-1154-2481
Kuniyasu, Hiroki

Mori, Shiori

Kishi, Shingo

Sugimoto, Sumire

Maehana, Tomoka https://orcid.org/0009-0001-0598-9466
Yamanaka, Shoichiro

Kawaguchi, Ryuji

Kimura, Fuminori
Funding

Funding for this research was provided by:

MEXT | Japan Society for the Promotion of Science (24K19730)
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Text and Data Mining valid from 2025-12-01

Version of Record valid from 2025-12-01
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Article History

Received: 5 March 2025

Revised: 1 October 2025

Accepted: 3 November 2025

First Online: 1 December 2025

Competing interests

: The authors declare no competing interests.

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