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Authors
Gao, Jincheng https://orcid.org/0000-0002-5618-0755
Bader, Almke https://orcid.org/0000-0003-2313-598X
Linder, Monika I.
Cheng, Jingyuan
Richter, Mathis https://orcid.org/0000-0002-3110-6137
da Costa, Raul https://orcid.org/0000-0001-9666-8301
Zehrer, Annette
Mitt, Karl https://orcid.org/0009-0006-0965-9903
Popper, Bastian
Meissner, Felix https://orcid.org/0000-0003-1000-7989
Wei, Xiang
de Vega Gómez, Enrique
Tatematsu, Megumi
Rohlfs, Meino
Frenz-Wiessner, Stephanie https://orcid.org/0000-0001-8862-3752
Kiziltug, Mehmet
Somekh, Ido
Yacobovich, Joanne
Steinberg-Shemer, Orna
Somech, Raz
Soehnlein, Oliver https://orcid.org/0000-0002-7854-0694
Schmid, Bettina
Klein, Christoph
Walzog, Barbara https://orcid.org/0000-0001-7729-6565
Maier-Begandt, Daniela https://orcid.org/0000-0001-8491-9820
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Funding
Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (CRC914 (project A02))
Deutsche Forschungsgemeinschaft (TRR332 (#449437943; project C03))
Deutsche Forschungsgemeinschaft (CRC914 (project A13))
Deutsche Forschungsgemeinschaft (TRR332 (#449437943; project A02))
Deutsche Forschungsgemeinschaft (TRR332 (#449437943; project B01))
Deutsche Forschungsgemeinschaft (CRC914 (projects A02 and Z03))
Deutsche Forschungsgemeinschaft (TRR332 (#449437943; project C03))
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Article History
Received: 8 May 2025
Revised: 31 October 2025
Accepted: 4 December 2025
First Online: 12 January 2026
Competing interests
: The authors declare no competing interests.
: All methods were performed in accordance with the relevant guidelines and regulations. All studies involving human samples were conducted in accordance with the Declaration of Helsinki. For isolation of human neutrophils, written informed consent was obtained from all volunteers prior to blood donation. The blood collection was approved by the ethics committee of the LMU Munich (No. 259-14). Written informed consent was obtained from the family of the patient to perform research on the samples of the patient and the father. Collection of blood samples to perform genome analyses at the Dr. von Hauner Children’s Hospital was approved by the ethics committee of the LMU Munich (No. 66-14). The use of iPS cells was authorized by the ethics committee of the LMU Munich (No. 24-0697 OMICS-SE). Adult zebrafish were raised and housed and experiments with zebrafish larvae were performed in accordance with animal protection standards of the LMU Munich and approved by the government of Upper Bavaria (Regierung von Oberbayern, No. 55.2-2532.Vet_02-17-21).
