Kinsella, Sinéad
Evandy, Cindy A.
Cooper, Kirsten
Kirsche, Erin
Warren, Makya
deRoos, Paul
Cardinale, Antonella
Iovino, Lorenzo
Granadier, David
Smith, Colton W. https://orcid.org/0000-0003-3669-8327
Hopwo, Kayla
Sullivan, Lucas B. https://orcid.org/0000-0002-6745-8222
Velardi, Enrico https://orcid.org/0000-0001-8383-0453
Dudakov, Jarrod A. https://orcid.org/0000-0001-6220-5632
Funding for this research was provided by:
American Society of Hematology (ASH Scholar)
U.S. Department of Health & Human Services | National Institutes of Health (R01-HL145276)
U.S. Department of Health & Human Services | National Institutes of Health (R01-HL165673)
U.S. Department of Health & Human Services | National Institutes of Health (U01-AI70035)
ASTCT New Investigator Award; Center of Execellence in Hematology Pilot Award.
V.E. was supported by grants from the Italian Association for Cancer Research, and by the Italian Ministry of Health.
Article History
Received: 14 November 2024
Revised: 10 November 2025
Accepted: 4 December 2025
First Online: 3 January 2026
Competing interests
: JAD, SK, and LI have submitted a patent application pending around these findings to promote thymus regeneration.
: All studies were performed in accordance with the relevant guidelines and regulations. Human tissue analysis was approved by the Ethics Committee of the Bambino Gesù Children’s Hospital (OPBG) under protocol number “1965_OPBG_2019. Informed consent was obtained from all participants (or their parents/legal guardians, where applicable) prior to inclusion in the study.