Funding for this research was provided by:
National Natural Science Foundation of China (82303558)
Chongqing Natural Science Foundation
Article History
Received: 24 April 2025
Revised: 28 October 2025
Accepted: 21 January 2026
First Online: 7 May 2026
Competing interests
: The authors declare no competing interests.
: Clinical specimens were collected from patients at the First Affiliated Hospital of University of Science and Technology of China. The storage, analysis, and disposal of these samples were conducted in compliance with the guidelines approved by the Ethics Committee of First Affiliated Hospital of University of Science and Technology of China. All animal procedures were performed following NIH guidelines and were approved by the Clinical Medical Ethics Committee of First Affiliated Hospital of University of Science and Technology of China.