Lin, Yu-Sen
Chang, Hsin-Yu
Hong, Wei-Ze
Chen, Jhen-Yu
Huang, Wei-Ching
Yuan, Ta-Tung
Ke, Tao-Wei
Tsai, Yuan-Yao
Chen, Te-Hong
Liang, Ji-An
Chao, Jui-I
Chao, K. S. Clifford https://orcid.org/0000-0002-7162-2566
Huang, Kevin Chih-Yang https://orcid.org/0000-0002-0266-3233
Funding for this research was provided by:
Ministry of Science and Technology, Taiwan (MOST110-2628-B-039-005)
Ministry of Science and Technology, Taiwan (MOST 111-2823-8-039-001)
Ministry of Science and Technology, Taiwan (MOST110-2314-B-039-032)
China Medical University Hospital (DMR-114-068)
Article History
Received: 24 April 2025
Revised: 7 December 2025
Accepted: 21 January 2026
First Online: 2 February 2026
Competing interests
: WCH and TTY were employed from HuniLife Biotechnology. The other authors declare that they have no conflicts of interest.
: All methods were carried out in accordance with the relevant ethical guidelines and regulations. The tissue collection study was reviewed and approved by the Internal Review Board (IRB) of China Medical University Hospital [Protocol number: CMUH105-REC2-072]. All the experimental procedures and animal protocols used were approved by the China Medical University Institutional Animal Care and Use Committee (Protocol No. CMUIACUC-2023-114) and followed all the relevant ethical regulations. All procedures were designed in accordance with the ethical standards of the China Medical University Institutional Animal Care and Use Committee to minimize the suffering and number of animals.
: Informed consent was obtained from all human participants or their legal guardians in accordance with the Declaration of Helsinki.