Ren, Likun
Lu, Rishang
Fei, Xiaobin
Chen, Shaojie
Liu, Peng
Liu, Songbai
zhu, Changhao
shen, Xiangchun https://orcid.org/0000-0002-4333-9106
Wang, Xing
Pan, Yaozhen https://orcid.org/0000-0001-5936-0965
Funding for this research was provided by:
National Natural Science Foundation of China (82560464)
National Natural Science Foundation of China (82460507)
Department of Health of Guizhou Province (gzwkj2024-373)
Guizhou Science and Technology Department (Qiankehe Basic-ZK[2024]GNRH230)
Guizhou Science and Technology Department (ZK[2024]066)
Guizhou Medical University (gyfynsfc[2024]-54)
Article History
Received: 2 February 2025
Revised: 17 December 2025
Accepted: 10 February 2026
First Online: 26 February 2026
Competing interests
: The authors declare no competing interests.
: This study was approved by the Human Ethics Committee of the Affiliated Hospital of Guizhou Medical University (2019 Ethical Review No. 073) and the Animal Ethics Committee of Guizhou Medical University (No.19000672). All participants were informed of the study’s purpose and provided written informed consent. All methods were performed in accordance with the relevant guidelines and regulations.
: All co-authors have consented to the version of the manuscript for publication.