Zhang, Yifan https://orcid.org/0000-0002-4641-3412
Yu, Zhaojun
Li, Yadong
Luo, Mayao
Hou, Wenli
Li, Sangsang
He, Jiapeng
Lv, Shidong https://orcid.org/0000-0002-6875-7697
Wei, Qiang https://orcid.org/0000-0001-5925-6922
Hu, Hailiang https://orcid.org/0000-0001-9205-1603
Article History
Received: 29 April 2025
Revised: 18 January 2026
Accepted: 16 February 2026
First Online: 27 February 2026
Competing interests
: The authors declare no competing interests.
: This study was approved by the Ethics Committee of Nanfang Hospital, Southern Medical University (No. NFEC-2022-299). Written informed consent was obtained from all patients for the use of their tumor tissue samples and clinical data for research purposes. Patient-derived clinical data were fully anonymized with encrypted storage separating personally identifiable information from research datasets. For the animal experiments, all procedures were carried out in accordance with the recommendations of the Southern University of Science and Technology Laboratory Animal Welfare Ethics Review Committee.