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UPR/ATF4/Noxa pathway overactivation through SERCA2 inhibition or ONC201 treatment combined with ABT-737 triggers apoptosis in chemoresistant ovarian cancer cells and patient-derived tumor organoids

Crossref DOI link: https://doi.org/10.1038/s41419-026-08559-7

Published Online: 2026-03-27

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Messaoudi, Sahra

Florent, Romane

Weiswald, Louis-Bastien https://orcid.org/0000-0001-6935-100X
Desmartin, Guillaume

Lecouflet, Lucie

Lohard, Steven

Grunchec, Léa

Abeilard, Edwige

Guillamin, Marilyne

Divoux, Jordane

Goudergues, Benoît

Brotin, Emilie

Dolivet, Enora

Poulain, Laurent

N’Diaye, Monique https://orcid.org/0000-0001-8867-0778
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Text and Data Mining valid from 2026-03-27

Version of Record valid from 2026-05-07
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Article History

Received: 28 May 2025

Revised: 27 January 2026

Accepted: 6 March 2026

First Online: 27 March 2026

Competing interests

: The authors declare no competing interests.

: All methods were performed in accordance with the relevant guidelines and regulations.

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