Wang, Chenyue
Lu, Qiutian
Cao, Lianbao
Zeng, Simeng
Gao, Zihan
Yang, Yinglong
Liu, Xiaowen
Gao, Shanshan https://orcid.org/0009-0007-0216-4745
Dong, Chao https://orcid.org/0000-0002-7645-2025
Funding for this research was provided by:
National Natural Science Foundation of China (82202858)
National Natural Science Foundation of China (82401944)
National Natural Science Foundation of China (82203149)
China Association for Science and Technology (2021QNRC001)
Natural Science Foundation of Shandong Province (ZR2022QH009)
Natural Science Foundation of Shandong Province (ZR2023QH521)
Natural Science Foundation of Shandong Province (ZR2021QH349)
Article History
Received: 13 May 2025
Revised: 12 February 2026
Accepted: 9 March 2026
First Online: 18 March 2026
Competing interests
: The authors declare no competing interests.
: The study involving laboratory animal and human participants was approved by the Science and Technology Ethics Committee of School of Public Health, Shandong University and the ethics committee of The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital. All methods including laboratory animal experiments were rigorously performed in accordance with the regulations of institutional animal care. Fully informed consent was obtained from all human participants involved in this research, including specific consent for the experimental use of their tissue samples.